解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Six new compounds, colletobredins A-D (1-4) and colletomelleins A and B (5 and 6), along with 12 previously identified compounds, were isolated from the culture broth of Colletotrichum aotearoa BCRC 09F0161, a fungal endophyte residing in the leaves of an endemic Formosan plant Bredia oldhamii Hook. f. (Melastomatacea...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1054285
更新日期:2016-01-01 00:00:00
abstract::In this study, the anti-tumour-promoting and thermal-induced protein denaturation inhibitory activities of β-sitosterol (1) and lupeol (2), isolated from Diospyros lotus L., were explored. Compound 1 showed a marked concentration-dependent inhibition against 12-O-tetradecanoylphorbol-13-acetate (20 ng/32 pmol)-induced...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1046381
更新日期:2016-01-01 00:00:00
abstract::Aedes aegypti is a primary vector of dengue, a mosquito-borne viral disease infecting 50-100 million people every year. Here, we biosynthesised mosquitocidal silver nanoparticles (AgNP) using the aqueous leaf extract of Crotalaria verrucosa. The green synthesis of AgNP was studied by UV-vis spectroscopy, SEM, EDX and ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1074230
更新日期:2016-01-01 00:00:00
abstract::A new rare lumazine peptide, penilumamide E (1), together with 13 known compounds (2-14) were isolated from the fungus Aspergillus terreus. Their structures were identified by spectroscopic techniques. The relative configuration of 1 was confirmed by single-crystal X-ray diffraction analysis. Compound 10 exhibited ant...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1101107
更新日期:2016-01-01 00:00:00
abstract::In the case of Achillea wilhelmsii, 30 compounds were identified representing 94.48% of the total oil with a yield of 0.82% w/w. The major constituents of the oil were described as α-thujene (6.11%), α-pinene (5.11%), sabinene (5.23%), p-cymene (7%), 1,8-cineole (6%), linalool (10%), camphor (8.43%), thymol (18.98%) a...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.953949
更新日期:2015-02-01 00:00:00
abstract::This article presents the very first phytochemical investigation on new species Tripleurospermum insularum Inceer & Hayırlıoglu-Ayaz. The volatile profile of odorous parts of the plant was analysed by GC/MS, and compounds were identified in headspace and essential oil obtained from aerial parts, representing 70.81% an...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.968156
更新日期:2015-02-01 00:00:00
abstract::Chemical investigation of the aerial parts of Uvaria rufa (Dunal) Blume collected from Vietnam yielded one new lignan glycoside, ufaside (1), along with six known compounds, oxoanolobine (2), ergosta-4,6,8(14),22-tetraen-3-one (3), catechin (4), epicatechin (5), daucosterol (6) and glutin-5-en-3-one (7). Their chemica...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.971790
更新日期:2015-02-01 00:00:00
abstract::The chemical composition of three rockrose Cistus species, Cistus monspeliensis, Cistus libanotis and Cistus villosus, collected in Tunisia, was studied by HPTLC, focusing on the terpenes and phenols constituents. Diterpenes of Cistus are important as the main constituents of the leaf sticky aromatic resin, known as l...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.947486
更新日期:2015-02-01 00:00:00
abstract::This study describes the seasonal composition and the antibacterial, antioxidant and anticholinesterase activity of the essential oil from Eugenia brasiliensis leaves. Analysis by using GC allowed the identification of 40 compounds. It was observed that the monoterpenes varied more (42%) than the sesquiterpenes (14%),...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.958736
更新日期:2015-02-01 00:00:00
abstract::The anti-atherogenic potentials of total ginger (Zingiber officinale) extract (TGE) or curcuminoids extracted from turmeric (Curcuma longa), members of family Zingiberaceae, were compared in hypercholesterolaemia. Rabbits were fed either normal or atherogenic diet. The rabbits on atherogenic diet received treatments w...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.957699
更新日期:2015-01-01 00:00:00
abstract::Tryptamine derivatives such as tryptamine and bacillamides were strong algicidal compounds promising in controlling harmful algae blooms, but their bioactivity and application researches were hindered by extremely low natural production rates. This study found an induced production of algicidal tryptamine derivatives ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1005619
更新日期:2015-01-01 00:00:00
abstract::Nine compounds were isolated from Nocardia sp. YIM 64630, and their structures were elucidated as 5'-O-acetyl-2'-deoxyuridine (1), 22E,24R-5α,6α-epoxyergosta-8(14),22-diene-3β,7α-diol (2), 22E,24R-5α,6α-epoxyergosta-8,22-diene-3β,7α-diol (3), 22E,24R-ergosta-7,22-diene-3β,5α,6β-triol (4), 5α,8α-epidioxyergosta-6,22-di...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.964713
更新日期:2015-01-01 00:00:00
abstract::Protein kinase C (PKC) plays a key role in neurotransmission in the central nervous system, and targeting PKC domain is considered as a strategy to modulate the anaesthetic effects. In this study, we described a synthetic pipeline to perform high-throughput virtual screening against a large library of 3D structural na...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.955491
更新日期:2015-01-01 00:00:00
abstract::One new briarane-type diterpenoid, dichotellide V (1), along with four known analogues, gemmacolide N (2), dichotellide J (3), junceelin A (4) and junceellolide A (5), was isolated from the South China Sea gorgonian Dichotella gemmacea. All of the isolated compounds (1-5) were established by comprehensive analysis of ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.987774
更新日期:2015-01-01 00:00:00
abstract::α-Mangostin is the major prenylated xanthone from Garcinia mangostana and it has been used also in recent times as starting material for the semisynthetic preparation of various biologically active derivatives. Its structure is characterised by the presence of few functional groups amenable to chemical manipulations, ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.986729
更新日期:2015-01-01 00:00:00
abstract::This study was aimed at characterising the secondary metabolites responsible for antibacterial and antioxidant activities of Acalypha wilkesiana. Purification of the defatted methanol leaves extract was guided by the DPPH free radical scavenging assay as well as by evaluation of the antibacterial activity against four...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.983105
更新日期:2015-01-01 00:00:00
abstract::Mahuang Fuzi Xixin (MFX), a classic recipe in traditional Chinese medicine, belongs to an exterior-relieving formula. For quality control of the MFX products, qualitative analysis using ultra-high performance liquid chromatography with diode-array detector-tandem mass spectrometry (UPLC-PDA-MS/MS) was undertaken. Six ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.983104
更新日期:2015-01-01 00:00:00
abstract::Botryodiplodia theobromae Pat. belongs to the endophytic fungi that live within the tissues of medicinal plants and produce bioactive natural products. The endophyte was isolated from the leaves of Dracaena draco L. The LC-MS-based metabolite fingerprinting of the ethyl acetate extract of B. theobromae with antibacter...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1012715
更新日期:2015-01-01 00:00:00
abstract::The antibacterial activity of essential oil and methanolic extract of Teucrium polium was determined against Pseudomonas aeruginosa, Pantoea agglomerans, Brenneria nigrifluens, Rhizobium radiobacter, Rhizobium vitis, Streptomyces scabies, Ralstonia solanacearum, Xanthomonas campestris and Pectobacterium cartovorum by ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.1000320
更新日期:2015-01-01 00:00:00
abstract::This study describes the in vitro inhibition of protein denaturation of extract/fractions of Withania somnifera and isolated withanolides including 20β hydroxy-1-oxo(22R)-witha-2,5,24 trienolide (1), (20R,22R-14α,20α)-dihydroxy-1-oxowitha-2,5,16,24 tetraenolide (2). The results showed that the extract/fractions of the...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1007138
更新日期:2015-01-01 00:00:00
abstract::A new citromycetin analogue, ascomycotin A (1), together with eight known compounds, wortmannilactone E (2), orcinol (3), orsellinic acid (4), isosclerone (5), (3R,4S)-( - )-4-hydroxymellein (6), diorcinol (7), chaetocyclinone B (8) and 2,5-dimethoxy-3,6-di(p-methoxypheny1)-1,4-benzoquinone (9), was isolated from the ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.988620
更新日期:2015-01-01 00:00:00
abstract::Three biflavonoid glycosides, named carinoside B, C and D (1, 2 and 3, respectively), were isolated from the n-BuOH crude extract of the aerial part of Lomatogonium carinthiacum (Wulfen) Rchb (L. carinthiacum). The structures of 1, 2 and 3 were elucidated by spectroscopic methods, including UV, IR, HR-ESI-MS and exten...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1025399
更新日期:2015-01-01 00:00:00
abstract::This study was designed to characterise the effects of evodiamine on intestinal contractility and reveal the correlated mechanisms. Evodiamine (2.5-80.0 μM) increased normal jejunal contractility and jejunal hypocontractility established under a variety of experimental conditions. Evodiamine-exerted stimulatory effect...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.947485
更新日期:2015-01-01 00:00:00
abstract::Euphorbia hirta (L.) plant is traditionally used in Malaysia for the treatment of gastrointestinal, bronchial and respiratory ailments caused by nosocomial infectious agents. Bioactivity-guided fractionation of the methanol extract of the aerial parts of E. hirta and analysis using high-performance liquid chromatograp...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.999242
更新日期:2015-01-01 00:00:00
abstract::Machaerium, in the family Fabaceae, predominantly is a genus of a Neotropical distribution of trees, shrubs, and lianas occurring from southern Mexico to Brazil and northern Argentina and as far as South America. Several Machaerium species are widely used in traditional medicine and are considered to have multiple med...
journal_title:Natural product research
pub_type: 杂志文章,评审
doi:10.1080/14786419.2014.1003062
更新日期:2015-01-01 00:00:00
abstract::Three new phenanthrenone constituents, trigoxyphins U-W (1, 7 and 9), together with eight known ones, trigoxyphin M (2), 6,9-O-dimethyltrigonostemone (3), trigonstemone (4), thrigonosomone B (5), trigonochinene E (6), actephiiol A (8), epiactephilol A (10) and neoboutomannin (11), were obtained from the methanol extra...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1009066
更新日期:2015-01-01 00:00:00
abstract::GC/FID and GC-MS analysis revealed germacrene D, bicyclogermacrene, α-cadinol and cubenol as major compounds from aril. Germacrene D, bicyclogermacrene, trans-caryophyllene and δ-elemene are major compounds in fruits. Germacrene D, spathulenol, trans-caryophyllene and caryophyllene oxide are major compounds in leaves....
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.987145
更新日期:2015-01-01 00:00:00
abstract::Cathepsin B (catB) is a cysteine protease involved in tumour progression and represents a potential therapeutic target in cancer. Among the 15 evaluated extracts from cerrado biome, Myrcia lingua Berg. (Myrtaceae) extract demonstrated to be a source of compounds with potential to inhibit catB. Using bioactivity-guided...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.1002404
更新日期:2015-01-01 00:00:00
abstract::Three species of the genus Homalium - e.g. Homalium nepalense, Homalium tomentosum and Homalium zeylanicum (Flacourtiaceae) - are recorded in India which are confined to the Eastern Ghat hill ranges. While H. zeylanicum is the IUCN red-listed medium-sized tree, the other two are endangered species of medicinal signifi...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.987142
更新日期:2015-01-01 00:00:00
abstract::This manuscript describes the antioxidant activity of essential oil of Cinnamon (Cinnamomum zeylanicum) bark extracted by supercritical fluid extraction (SCFE), hydro distillation and steam distillation. The cinnamon bark essential oil exhibited a wide range of total phenolic contents, total flavonoid contents, reduci...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.1002088
更新日期:2015-01-01 00:00:00
abstract::Cedronella canariensis is a lemon-scented species of the family Lamiaceae endemic to the Canary Islands where it is used in the traditional medicine to prepare infusions or inhalations for anti-catarrhal, tonic, diuretic, hypoglycaemiant, hypotensive, anti-inflammatory and decongestant of the respiratory tract. In thi...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.994213
更新日期:2015-01-01 00:00:00
abstract::From the fruit of Pandanus tectorius Parkinson ex Du Roi, one new (1) and six known aldehyde compounds (2-7) were isolated by various chromatography methods. Based on their spectroscopic data, these compounds were identified as (Z)-4-hydroxy-3-(4-hydroxy-3-methylbut-2-en-1-yl) benzaldehyde (1), p-hydroxybenzaldehyde (...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.1003929
更新日期:2015-01-01 00:00:00
abstract::Lycopus europaeus L. leaves water extract (LEL) was subjected to phytochemical analysis, and evaluated for its antibacterial and antioxidant effects. Antibacterial activity testing was performed on Staphylococcus aureus clinical strains from catheter-related and skin infections by broth microdilution test. LEL showed ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1010086
更新日期:2015-01-01 00:00:00
abstract::Three new (1-3) and 17 known (4-20) iridoid and secoiridoid glycosides were isolated from a methanol extract of the rhizomes and roots of Gentiana scabra. Their chemical structures were elucidated from 1D and 2D NMR, IR absorption, and HR-ESI-MS spectra, as well as comparisons of these data with reported values. The e...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1013955
更新日期:2015-01-01 00:00:00
abstract::The study examined the radioprotective activity of an aqueous extract from Pleurotus ostreatus mycelium administered to Balb/c mice. Male mice were whole-body irradiated on day 0 ((60)Co, at 0.43 Gy/min) and divided into two groups. The extract was administered intraperitoneally to one group (100 mg/kg) on days - 10 t...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.983918
更新日期:2015-01-01 00:00:00
abstract::Essential oils from the leaves, twigs and barks of Bocageopsis pleiosperma Maas were obtained by using hydrodistillation and analysed by using gas chromatography coupled to mass spectrometry. Several compounds (51) were detected and identified, being β-bisabolene the main component in all aerial parts of the plant, wi...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.996148
更新日期:2015-01-01 00:00:00
abstract::Plants, in their life cycle, are usually exposed to various kinds of non-biological stresses including heavy metals. One of these heavy metals is nickel which affects many physiological processes of plants. Studies have shown that the changes in planting conditions can affect the qualitative and quantitative features ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.913240
更新日期:2014-01-01 00:00:00
abstract::A new phenolic glycoside, 6-O-(4'-hydroxy-3',5'-dimethoxybenzoyl)-d-glucopyranose (4), and nine known compounds (1-3 and 5-10) were isolated from Juglans mandshurica Maxim. Compound structures were elucidated by NMR, HR-ESI-MS and acid hydrolysis. Compounds 5 and 6 are reported from this genus for the first time. Amon...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.902946
更新日期:2014-01-01 00:00:00
abstract::Chemical investigation of the mycelial extract of a mixed culture of two marine alga-derived fungal strains of the genus Aspergillus has yielded one new cyclotripeptide, psychrophilin E (1), the recently reported oxepin-containing alkaloids, protuboxepin A (2) and oxepinamide E (3), together with three other polyketid...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.880911
更新日期:2014-01-01 00:00:00
abstract::To obtain more accessible oxidative stress inhibitors, a series of novel spin-labelled derivatives of 3-hydroxybutanolide (2a-d, 3a-d) with the natural active compound (kinsenoside) as the lead compound were designed, synthesised from the nitroxide free radical piperidine (pyrroline) and the main structural unit of ki...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.903477
更新日期:2014-01-01 00:00:00